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Today’s early best bets to target: Top picks for 2025 MLB Playoffs, college football betting today

October 17, 2025
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The Toronto Blue Jays continued the trend of the road team winning every game in the American League Championship Series with their 8-2 victory over the Seattle Mariners to even the series on Thursday. However, the SportsLine model predicts this trend ends on Friday, making the Mariners defeating the Blue Jays at home one of its Friday best bets in a 6:08 p.m. ET start. The model is also backing plenty of offense in No. 2 Miami vs. Louisville, picking Over 50.5 points, and has an afternoon soccer best bet as well. The model predicts Espanyol to defeat Real Oviedo in La Liga action at 3 p.m. ET. 

Click here to bet today’s games with the latest Fanatics Sportsbook promo code, which allows new users to bet and get up to $2,000 in No Sweat Bets in FanCash.

Whether you’re looking into MLB betting, college football betting, soccer betting or anything else on the Friday sports schedule, there are a number of online sports betting options, and our team can help point you in the right direction. Our computer model and experts will weigh in on all of the biggest events every day, and they’re offering their top sports betting picks right now.

Friday college football best bets 

Game: Miami vs. Louisville (Friday 7 p.m. ET)The Pick: Over 50.5 points (-110)

Both ACC teams made two of the biggest quarterback acquisitions from the transfer portal heading into this season, with Miami signing Carson Beck from Georgia and Louisville adding Miller Moss from USC. Moss has thrown for 1,358 yards, including more than 300 yards in three straight games, and Louisville is averaging 32.3 ppg this season, which ranks 35th in the nation. Beck has thrown for 1,213 yards with Miami averaging 32.5 ppg, slightly ahead at No. 32 in the country. Both teams have scored at least 26 points in every game this season, a trend alone that would bring this game Over its total. Given the experienced quarterbacks leading these successful offensive teams, the model projects the Over to hit in 73% of simulations.

Bet Miami vs. Louisville at FanDuel, where new users get $300 in bonus bets with a winning $5 wager.

More college football best bets

Blue Jays vs. Mariners best bets

Game: Toronto Blue Jays vs. Seattle Mariners, ALCS, Game 5 (6:08 p.m. ET)The Pick: Mariners to win (-104)

Game 5 features the same pitching matchup as Game 1, a contest the Mariners won, 3-1. Bryce Miller returns to the mound for Seattle against Toronto’s Kevin Gausman, and Miller allowed just one run on two hits in six innings in Game 1. The Mariners entered the postseason after one of the best final few weeks of a regular season in baseball history, going 17-4 over their final 21 games, including a 17-1 stretch. That success has carried into the postseason with a 5-2 start before dropping back-to-back contests. The Mariners had the second-best home record in baseball (51-30) this season, and the model projects Seattle to win in 56% of simulations.

Bet Mariners vs. Blue Jays at Caesars Sportsbook, where new users get 20 100% profit boosts with the promo code CBS20X:

More MLB best bets

Friday soccer best bets

Game: Espanyol vs. Real Oviedo, La Liga (3 p.m. ET)The Pick: Espanyol (+150) to defeat Real Oviedo on the 90-minute moneyline

Real Oviedo will host Espanyol at 3 p.m. ET in La Liga action before a busy weekend slate. Espanyol are ninth at 3-3-2 this year, while Real Oviedo are 17th at 2-0-6 in the league this season. Real Oviedo are coming off a 2-0 loss to Levante on Oct. 4 in their last La Liga match for their fourth loss in five contests since the start of September. They’ve only scored three goals over those five matches. Espanyol are winless over their last four matches, but they had two draws and the two losses came to teams currently in the top four on the table. The model projects Espanyol to win on the 90-minute line in 48% of simulations, showing strong value at +155 at DraftKings.

Bet Espanyol vs. Real Oviedo at DraftKings Sportsbook, where new users can get $300 in bonus bets if your first bet wins, plus three months of NBA League Pass free.



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