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Butler vs. St. John’s prediction, odds, time, spread: 2026 college basketball picks from proven model

January 28, 2026
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The Butler Bulldogs will look to win their fourth game in a row when they take on the 25th-ranked St. John’s Red Storm in a key Big East Conference matchup on Wednesday night. Butler is coming off an 87-76 win over Marquette on Friday, while St. John’s downed Xavier 88-83 on Saturday. The Bulldogs (13-7, 4-5 Big East), who are tied for fifth in the conference, are 1-4 on the road this season. The Red Storm (15-5, 8-1 Big East), who are second in the Big East, are 9-2 on their home court.

Tipoff from Madison Square Garden in New York is set for 7 p.m. ET. St. John’s is a 12.5-point favorite in the latest Butler vs. St. John’s odds from DraftKings Sportsbook, while the over/under for total points scored is 160.5. Before making any St. John’s vs. Butler picks, check out the men’s college basketball predictions and betting advice from the SportsLine Projection Model.

New users can target the DraftKings promo code, which offers $300 in bonus bets if your $5+ bet wins:

The SportsLine Projection Model simulates every college basketball game 10,000 times and it enters Week 13 on a sizzling 10-1 run on its top-rated over/under college basketball picks dating back to last season, and it is on a 6-0 roll on college basketball side picks. Anyone following its college basketball betting advice at sportsbooks and on betting apps could have seen strong returns.

Now, the model has simulated Butler vs. St. John’s 10,000 times and just revealed its coveted men’s college basketball picks and betting predictions. You can head to SportsLine now to see the model’s picks. Here are several men’s college basketball odds and men’s college basketball betting lines for St. John’s vs. Butler:

Butler vs. St. John’s spread:    

St. John’s -12.5 at DraftKings Sportsbook

Butler vs. St. John’s over/under:    

160.5 points

Butler vs. St. John’s money line:    

St. John’s -1020, Butler +651

Butler vs. St. John’s picks:    

See picks at SportsLine

Butler vs. St. John’s streaming:

Fubo (Try for free)  

New users can check out the latest bet365 bonus code to get $200 in bonus bets after placing a $5 bet:

How to make Butler vs. St. John’s picks

SportsLine’s model is going Under on the total (160.5 points). The Under has hit in eight of the last 10 meetings between the teams, including in each of the last five games. Butler is 5-5 against the spread in its last 10 games, while St. John’s is 4-2 ATS in its last six.

The model projects the Bulldogs to have three players register 10 points or more, including Finley Bizjack’s projected 16.3 points. The Red Storm, meanwhile, are projected to have five players score 10.4 or more points, led by Zuby Ejiofor, who is projected to score 17.6 points. The model projects a combined total of 156 points as the Under clears in nearly 70% of simulations.

The model also says one side of the spread hits well over 50% of the time. You can only see that pick at SportsLine.

So who wins Butler vs. St. John’s, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the Butler vs. St. John’s spread to back, all from the advanced model that has simulated this game 10,000 times, and find out.



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