There are three ranked matchups this weekend, starting with No. 1 Ohio State on the road against No. 17 Illinois and No. 8 Alabama also on the road against No. 14 Missouri, both at noon ET.
At 3:30 p.m. ET, No. 7 Indiana and No. 3 Oregon clash in their first head-to-head matchup as Big Ten rivals. Both teams have at least a 60% chance to reach the College Football Playoff, even with a loss, according to ESPN Analytics.
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Texas Tech entered the top 10 for the first time since 2013, and No. 9 is their highest ranking since 2008, when they rose as high as No. 2. No. 16 Notre Dame and No. 25 Florida State are the only two-loss teams ranked this week.
Elsewhere, Florida is playing an AP top-10 opponent (No. 5 Texas A&M) for a fourth straight game, making them the first team to do so in the same regular season since 1968, according to ESPN Research.
All times Eastern. For latest lines, go to ESPN BET
No. 24 South Florida at North Texas -1.5Friday, 7:30 p.m., ESPN2
Records: South Florida 4-1, 2-1 vs. AP teams; North Texas 5-0, 0-0 vs. AP teamsOpening line: North Texas -1.5, O/U 66.5Money line: South Florida (-110); North Texas (-110)Over/under: 67.5 (O -105, U -115)
FPI Projection North Texas by 0.8 points with a 53% probability to win game outright
No. 1 Ohio State -14.5 at No. 17 IllinoisSaturday, Noon, Fox
Records: Ohio State 5-0, 1-0 vs. AP teams; Illinois 5-1, 1-1 vs. AP teamsOpening line: Ohio State -16.5, O/U 48.5Money line: Ohio State (-700); Illinois (+450)Over/under: 50.5 (O -115, U -105)
FPI Projection Ohio State by 10.7 points with a 82% probability to win game outright
No. 8 Alabama -2.5 at No. 14 MissouriSaturday, Noon, ABC
Records: Alabama 4-1, 2-0 vs. AP teams; Missouri 5-0, 0-0 vs. AP teamsLine Movement Alert: Opened Alabama -5.5, O/U 54.5Money line: Alabama (-150); Missouri (+130)Over/under: 52.5 (O -120, U EVEN)
FPI Projection Alabama by 3.4 points with a 63% probability to win game outright
Pittsburgh at No. 25 Florida State -10.5Saturday, Noon, ESPN
Records: Pittsburgh 3-2, 0-0 vs. AP teams; Florida State 3-2, 1-1 vs. AP teamsOpening line: Florida State -9.5, O/U 58.5Money line: Pittsburgh (+300); Florida State (-400)Over/under: 58.5 (O -105, U -115)
FPI Projection Florida State by 8.1 points with a 77% probability to win game outright
Washington State at No. 4 Ole Miss -32.5Saturday, 12:45 p.m., SEC Network
Records: Washington State 3-2, 0-0 vs. AP teams; Ole Miss 5-0, 1-0 vs. AP teamsOpening line: Ole Miss -32.5, O/U 59.5Money line: OffOver/under: 59.5 (O -105, U -115)
FPI Projection Ole Miss by 34.7 points with a 98% probability to win game outright
No. 7 Indiana at No. 3 Oregon -7.5Saturday, 3:30 p.m., CBS
Records: Indiana 5-0, 1-0 vs. AP teams; Oregon 5-0, 1-0 vs. AP teamsOpening line: Oregon -7.5, O/U 54.5Money line: Indiana (+250); Oregon (-300)Over/under: 55.5 (O -105, U -115)
FPI Projection Oregon by 5.2 points with a 69% probability to win game outright
No. 6 Oklahoma at Texas -2.5Saturday, 3:30 p.m., ABC
Records: Oklahoma 5-0, 2-0 vs. AP teams; Texas 3-2, 0-1 vs. AP teamsOpening line: Texas -2.5, O/U 42.5Money line: Oklahoma (+120); Texas (-140)Over/under: 42.5 (O -115, U -105)
FPI Projection Texas by 2.8 points with a 61% probability to win game outright
Virginia Tech at No. 13 Georgia Tech -14.5Saturday, 3:30 p.m., ACC Network
Records: Virginia Tech 2-4, 0-1 vs. AP teams; Georgia Tech 5-0, 1-0 vs. AP teamsOpening line: Georgia Tech -14.5, O/U 55.5Money line: Virginia Tech (+475); Georgia Tech (-750)Over/under: 55.5 (O -115, U -105)
FPI Projection Georgia Tech by 9.4 points with a 80% probability to win game outright
NC State at No. 16 Notre Dame -21.5Saturday, 3:30 p.m., Peacock
Records: NC State 4-2, 0-0 vs. AP teams; Notre Dame 3-2, 0-2 vs. AP teamsOpening line: Notre Dame -22.5, O/U 62.5Money line: NC State (+1000); Notre Dame (-2000)Over/under: 61.5 (O -105, U -115)
FPI Projection Notre Dame by 19.5 points with a 92% probability to win game outright
No. 22 Iowa State -3.5 at ColoradoSaturday, 3:30 p.m., ESPN
Records: Iowa State 5-1, 1-0 vs. AP teams; Colorado 2-4, 0-1 vs. AP teamsOpening line: Iowa State -4.5, O/U 53.5Money line: Iowa State (-175); Colorado (+150)Over/under: 53.5 (O -105, U -115)
FPI Projection Iowa State by 3.3 points with a 63% probability to win game outright
Arkansas at No. 12 Tennessee -12.5Saturday, 4:15 p.m., SEC Network
Records: Arkansas 2-3, 0-2 vs. AP teams; Tennessee 4-1, 0-1 vs. AP teamsOpening line: Tennessee -12.5, O/U 69.5Money line: Arkansas (+380); Tennessee (-550)Over/under: 69.5 (O -105, U -115)
FPI Projection Tennessee by 10.7 points with a 83% probability to win game outright
Florida at No. 5 Texas A&M -7.5Saturday, 7 p.m., ESPN
Records: Florida 2-3, 1-2 vs. AP teams; Texas A&M 5-0, 1-0 vs. AP teamsOpening line: Texas A&M -8.5, O/U 47.5Money line: Florida (+230); Texas A&M (-280)Over/under: 46.5 (O -115, U -105)
FPI Projection Texas A&M by 6.7 points with a 74% probability to win game outright
Kansas at No. 9 Texas Tech -13.5Saturday, 7:30 p.m., Fox
Records: Kansas 4-2, 0-0 vs. AP teams; Texas Tech 5-0, 1-0 vs. AP teamsOpening line: Texas Tech -14.5, O/U 60.5Money line: Kansas (+450); Texas Tech (-700)Over/under: 60.5 (O -110, U -110)
FPI Projection Texas Tech by 7 points with a 74% probability to win game outright
No. 10 Georgia -3.5 at AuburnSaturday, 7:30 p.m., ABC
Records: Georgia 4-1, 1-1 vs. AP teams; Auburn 3-2, 0-2 vs. AP teamsOpening line: Georgia -3.5, O/U 46.5Money line: Georgia (-175); Auburn (+150)Over/under: 46.5 (O -115, U -105)
FPI Projection Georgia by 3.5 points with a 64% probability to win game outright
No. 15 Michigan at USC -2.5Saturday, 7:30 p.m., NBC
Records: Michigan 4-1, 0-1 vs. AP teams; USC 4-1, 0-1 vs. AP teamsOpening line: USC -1.5, O/U 57.5Money line: Michigan (+110); USC (-130)Over/under: 57.5 (O -115, U -105)
FPI Projection USC by 4.8 points with a 69% probability to win game outright
South Carolina at No. 11 LSU -8.5Saturday, 7:45 p.m., SEC Network
Records: South Carolina 3-2, 0-1 vs. AP teams; LSU 4-1, 1-1 vs. AP teamsOpening line: LSU -9.5, O/U 44.5Money line: South Carolina (+270); LSU (-340)Over/under: 44.5 (O -105, U -115)
FPI Projection LSU by 6.3 points with a 73% probability to win game outright
No. 18 BYU -1.5 at ArizonaSaturday, 8 p.m., ESPN2
Records: BYU 5-0, 0-0 vs. AP teams; Arizona 4-1, 0-1 vs. AP teamsOpening line: BYU -2.5, O/U 47.5Money line: BYU (-125); Arizona (+105)Over/under: 47.5 (O -110, U -110)
FPI Projection BYU by 5.1 points with a 70% probability to win game outright
No. 21 Arizona State at Utah -5.5Saturday, 10:15 p.m., ESPN
Records: Arizona State 4-1, 1-0 vs. AP teams; Utah 4-1, 0-1 vs. AP teamsOpening line: Utah -4.5, O/U 48.5Money line: Arizona State (+170); Utah (-200)Over/under: 48.5 (O -110, U -110)
FPI Projection Utah by 5.3 points with a 70% probability to win game outright
